This study aimed to characterise Egyptian desert vine flora and compare it with that of deserts in other \ncontinents such as Australia and North America. Specifically 5 common climbing desert plants (Citrullus colocynthis\nCocculus pendulus Cucumis prophetarum Pergularia tomentosa and Periploca angustifolia) were selected for this \nstudy. The floristic composition vegetation heterogeneity and chorological affinities of the associated species of the \nstudied climbing plants were quantitatively analysed. In general Leguminosae Convolvulaceae Cucurbitaceae and \nAsclepiadaceae are the most species-rich families of the climbing plants in Egypt. h e comparison of all desert climbing \nplants in Egypt to those found in the deserts of other continents (specifically the Australian Sonoran and Chihuahuan \ndeserts) revealed the same dominant plant families. the chorological analysis of the associated l ora indicated the \nabundance of the Saharo-Arabian chorotype within the major growth forms. Classification of the vegetation associated \nwith the 5 climbing plants yielded 4 vegetation groups each linked to 1 or more of the studied climbing plants. Both \nDCA and CCA were used to assess the soil-vegetation relationships; results indicated that gravel coarse sand Na+\n SO4-2 Cl- and NO3-\n were the most important factors for the distribution of the vegetation patterns of the studied desert vines.